A suicide bomber has detonated an explosives-packed car in west Kabul near a compound where Afghan elders will debate a security pact with the US next week.
At least six people were killed and 22 wounded in the blast, said Sediq Sediqqi, an Interior Ministry spokesman. He said the casualties included soldiers and civilians.
Around 2,500 tribal elders and civil leaders are expected to take part in an assembly known as a "loya jirga" next Thursday, to decide whether to accept the draft Bilateral Security Agreement between Afghanistan and the US.
Nasrullah, a witness, said: "I heard a big bang near the jirga site, later saw ambulances carrying people in blood. I saw at least three wounded in army uniforms."
Firefighters clear the area around where the car exploded A statement issued by the Afghan interior ministry said the attacker was being pursued by security forces shortly before the explosion.
"The attacker driving a vehicle had been identified and was being pursued by security forces. He detonated himself after police opened fire on his vehicle."
Earlier in the day, President Hamid Karzai called on the Taliban and their allies to join the assembly.
He said: "We invite them, please come to this national jirga of Afghanistan, raise your voice, raise your objection, and share your views."
The draft pact was hammered out in Kabul last month during a visit by US Secretary of State John Kerry.
But he left without a final deal as Afghan President Hamid Karzai said only a jirga had the authority to decide the contentious issues.
The car blew up in west Kabul These include a US demand to retain legal jurisdiction over its troops in Afghanistan, which would give them immunity from Afghan law. The request emerged as the main sticking point after Mr Kerry's visit.
The Taliban, whose government was toppled by a US-led invasion in 2001, has rejected the jirga and warned members that they would be punished as "traitors" if they endorsed the deal.
If the agreement is passed by both loya jirga and parliament, between 5,000 and 10,000 US troops would stay in Afghanistan to help fight al Qaeda remnants and train the national army.
Washington had been pushing for the agreement to be signed by the end of October to allow the US-led Nato coalition to plan the withdrawal of its 75,000 combat troops by December 2014.
The collapse of a similar security agreement with Iraq in 2011 led to the US pulling all its troops out of the country, which is currently suffering its worst sectarian violence since 2008.
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